Cargando…

Use of the Local False Discovery Rate for Identification of Metabolic Biomarkers in Rat Urine Following Genkwa Flos-Induced Hepatotoxicity

Metabolomics is concerned with characterizing the large number of metabolites present in a biological system using nuclear magnetic resonance (NMR) and HPLC/MS (high-performance liquid chromatography with mass spectrometry). Multivariate analysis is one of the most important tools for metabolic biom...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zuojing, Li, Qing, Geng, Lulu, Chen, Xiaohui, Bi, Kaishun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699555/ https://www.ncbi.nlm.nih.gov/pubmed/23844011 http://dx.doi.org/10.1371/journal.pone.0067451

Ejemplares similares

Isolation of anticancer constituents from flos genkwa (Daphne genkwa Sieb.et Zucc.) through bioassay-guided procedures
por: Li, Simeng, et al.
Publicado: (2013)

Full Toxicity Assessment of Genkwa Flos and the Underlying Mechanism in Nematode Caenorhabditis elegans
por: Qiao, Yan, et al.
Publicado: (2014)

Yuanhuacin and Related Anti-Inflammatory and Anticancer Daphnane Diterpenes from Genkwa Flos—An Overview
por: Bailly, Christian
Publicado: (2022)

Anti-herpes Activity of Vinegar-processed Daphne genkwa Flos Via Enhancement of Natural Killer Cell Activity
por: Uyangaa, Erdenebileg, et al.
Publicado: (2015)

Analytical quality by design methodology for botanical raw material analysis: a case study of flavonoids in Genkwa Flos
por: Kim, Min Kyoung, et al.
Publicado: (2021)

Empirical Bayes estimation of posterior probabilities of enrichment: A comparative study of five estimators of the local false discovery rate
por: Yang, Zhenyu, et al.
Publicado: (2013)

Quantitative metabolomics for investigating the value of polyamines in the early diagnosis and therapy of colorectal cancer
por: Liu, Ran, et al.
Publicado: (2017)

Revealing the Toxicity-Enhancing Essence of Glycyrrhiza on Genkwa Flos Based on Ultra-high-performance Liquid Chromatography Coupled With Quadrupole-Orbitrap High-Resolution Mass Spectrometry and Self-Assembled Supramolecular Technology
por: Yang, Yuqin, et al.
Publicado: (2021)

False discovery rate control in cancer biomarker selection
por: Li, Zhaoming
Publicado: (2023)

Chemical Pattern Recognition for Quality Analysis of Lonicerae Japonicae Flos and Lonicerae Flos Based on Ultra-High Performance Liquid Chromatography and Anti-SARS-CoV2 Main Protease Activity
por: Gu, Lifei, et al.
Publicado: (2022)

Lonicerae Japonicae Flos and Lonicerae Flos: A Systematic Pharmacology Review
por: Li, Yujie, et al.
Publicado: (2015)

An Investigation on the Quantitative Structure-Activity Relationships of the Anti-Inflammatory Activity of Diterpenoid Alkaloids
por: Li, Xiao, et al.
Publicado: (2017)

Avoiding false discovery in biomarker research
por: Patel, Pranali, et al.
Publicado: (2016)

Bioequivalence and Population Pharmacokinetic Modeling of Two Forms of Antibiotic, Cefuroxime Lysine and Cefuroxime Sodium, after Intravenous Infusion in Beagle Dogs
por: Zhao, Longshan, et al.
Publicado: (2012)

Lonicerae japonicae flos and Lonicerae flos: a systematic review of ethnopharmacology, phytochemistry and pharmacology
por: Li, Yuke, et al.
Publicado: (2019)

Comparison of anti-inflammatory effects of Lonicerae Japonicae Flos and Lonicerae Flos based on network pharmacology
por: Gao, Yu, et al.
Publicado: (2021)

Local false discovery rate facilitates comparison of different microarray experiments
por: Hong, Wan-Jen, et al.
Publicado: (2009)

Comprehensive Comparative Analysis of Local False Discovery Rate Control Methods
por: Kim, Shin June, et al.
Publicado: (2021)

False Discovery Rate Control in Cancer Biomarker Selection Using Knockoffs
por: Shen, Arlina, et al.
Publicado: (2019)

Metabolomics of Aurantio-Obtusin-Induced Hepatotoxicity in Rats for Discovery of Potential Biomarkers
por: Xu, Longlong, et al.
Publicado: (2019)

Polyamine Metabolites Profiling for Characterization of Lung and Liver Cancer Using an LC-Tandem MS Method with Multiple Statistical Data Mining Strategies: Discovering Potential Cancer Biomarkers in Human Plasma and Urine
por: Xu, Huarong, et al.
Publicado: (2016)

Efficient Plant Regeneration System from Leaf Explant Cultures of Daphne genkwa via Somatic Embryogenesis
por: Ku, Seong Sub, et al.
Publicado: (2023)

A Simple, Rapid, and Practical Method for Distinguishing Lonicerae Japonicae Flos from Lonicerae Flos
por: Zhang, Fang, et al.
Publicado: (2019)

Hepatotoxicity in immune checkpoint inhibitors: A pharmacovigilance study from 2014–2021
por: Xu, Ze, et al.
Publicado: (2023)

A constrained polynomial regression procedure for estimating the local False Discovery Rate
por: Dalmasso, Cyril, et al.
Publicado: (2007)

False discovery rates in spectral identification
por: Jeong, Kyowon, et al.
Publicado: (2012)

Controlling the Rate of GWAS False Discoveries
por: Brzyski, Damian, et al.
Publicado: (2017)

Daphne Genkwa Sieb. et Zucc. Water-Soluble Extracts Act on Enterovirus 71 by Inhibiting Viral Entry
por: Chang, Chia-Wen, et al.
Publicado: (2012)

Improved results in proteomics by use of local and peptide-class specific false discovery rates
por: Sennels, Lau, et al.
Publicado: (2009)

False discovery rates: a new deal
por: Stephens, Matthew
Publicado: (2017)

4497 Accessible False Discovery Rate Computation
por: Hollister, Megan C, et al.
Publicado: (2020)

The functional false discovery rate with applications to genomics
por: Chen, Xiongzhi, et al.
Publicado: (2019)

Local false discovery rate and minimum total error rate approaches to identifying interesting chromosomal regions
por: Sinha, Ritwik, et al.
Publicado: (2005)

Kerfdr: a semi-parametric kernel-based approach to local false discovery rate estimation
por: Guedj, Mickael, et al.
Publicado: (2009)

Local false discovery rate estimation using feature reliability in LC/MS metabolomics data
por: Chong, Elizabeth Y., et al.
Publicado: (2015)

Estimating the local false discovery rate via a bootstrap solution to the reference class problem
por: Abbas-Aghababazadeh, Farnoosh, et al.
Publicado: (2018)

Investigation on Flos Trollii: Constituents and bioactivities
por: YUAN, Ming, et al.
Publicado: (2013)

Design of Experiments-Based Optimization of Flavonoids Extraction from Daphne genkwa Flower Buds and Flavonoids Contents at Different Blooming Stages
por: Kim, Min-Kyoung, et al.
Publicado: (2022)

Identification of Daphne genkwa and Its Vinegar-Processed Products by Ultraperformance Liquid Chromatography–Quadrupole Time-of-Flight Mass Spectrometry and Chemometrics
por: Mi, Hongying, et al.
Publicado: (2023)

Classification and Authentication of Lonicerae Japonicae Flos and Lonicerae Flos by Using (1)H-NMR Spectroscopy and Chemical Pattern Recognition Analysis
por: Liu, Kaishuang, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9crtbeco34kvnjsqf66hs94fil