Using High-Throughput Sequencing to Leverage Surveillance of Genetic Diversity and Oseltamivir Resistance: A Pilot Study during the 2009 Influenza A(H1N1) Pandemic

BACKGROUND: Influenza viruses display a high mutation rate and complex evolutionary patterns. Next-generation sequencing (NGS) has been widely used for qualitative and semi-quantitative assessment of genetic diversity in complex biological samples. The “deep sequencing” approach, enabled by the enor...

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Detalles Bibliográficos
Autores principales: Téllez-Sosa, Juan, Rodríguez, Mario Henry, Gómez-Barreto, Rosa E., Valdovinos-Torres, Humberto, Hidalgo, Ana Cecilia, Cruz-Hervert, Pablo, Luna, René Santos, Carrillo-Valenzo, Erik, Ramos, Celso, García-García, Lourdes, Martínez-Barnetche, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699567/
https://www.ncbi.nlm.nih.gov/pubmed/23843978
http://dx.doi.org/10.1371/journal.pone.0067010

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