Chronic Central Administration of Ghrelin Increases Bone Mass through a Mechanism Independent of Appetite Regulation

Leptin plays a critical role in the central regulation of bone mass. Ghrelin counteracts leptin. In this study, we investigated the effect of chronic intracerebroventricular administration of ghrelin on bone mass in Sprague-Dawley rats (1.5 μg/day for 21 days). Rats were divided into control, ghreli...

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Detalles Bibliográficos
Autores principales: Choi, Hyung Jin, Ki, Kyoung Ho, Yang, Jae-Yeon, Jang, Bo Young, Song, Jung Ah, Baek, Wook-Young, Kim, Jung Hee, An, Jee Hyun, Kim, Sang Wan, Kim, Seong Yeon, Kim, Jung-Eun, Shin, Chan Soo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699588/
https://www.ncbi.nlm.nih.gov/pubmed/23843943
http://dx.doi.org/10.1371/journal.pone.0065505

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