Posttranslational Modifications of the Histone 3 Tail and Their Impact on the Activity of Histone Lysine Demethylases In Vitro

Posttranslational modifications (PTMs) of the histone H3 tail such as methylation, acetylation and phosphorylation play important roles in epigenetic signaling. Here we study the effect of some of these PTMs on the demethylation rates of methylated lysine 9 in vitro using peptide substrates mimickin...

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Detalles Bibliográficos
Autores principales: Lohse, Brian, Helgstrand, Charlotte, Kristensen, Jan B. L., Leurs, Ulrike, Cloos, Paul A. C., Kristensen, Jesper L., Clausen, Rasmus P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699631/
https://www.ncbi.nlm.nih.gov/pubmed/23844048
http://dx.doi.org/10.1371/journal.pone.0067653

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