T Cell Activation Inhibitors Reduce CD8+ T Cell and Pro-Inflammatory Macrophage Accumulation in Adipose Tissue of Obese Mice

Adipose tissue inflammation and specifically, pro-inflammatory macrophages are believed to contribute to insulin resistance (IR) in obesity in humans and animal models. Recent studies have invoked T cells in the recruitment of pro-inflammatory macrophages and the development of IR. To test the role...

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Detalles Bibliográficos
Autores principales: Montes, Vince N., Turner, Michael S., Subramanian, Savitha, Ding, Yilei, Hayden-Ledbetter, Martha, Slater, Sonya, Goodspeed, Leela, Wang, Shari, Omer, Mohamed, Den Hartigh, Laura J., Averill, Michelle M., O’Brien, Kevin D., Ledbetter, Jeffrey, Chait, Alan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699637/
https://www.ncbi.nlm.nih.gov/pubmed/23844072
http://dx.doi.org/10.1371/journal.pone.0067709

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