Cargando…
Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients
The objective of the study was to evaluate the oncological and functional results of transoral laser microsurgery (TLM) in patients with supraglottic laryngeal squamous cell carcinoma. Between June 1980 and December 2006, 277 patients with squamous cell supraglottic carcinoma of all stages were trea...
Autores principales: | , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699705/ https://www.ncbi.nlm.nih.gov/pubmed/23306348 http://dx.doi.org/10.1007/s00405-012-2327-6 |
_version_ | 1782275442327158784 |
---|---|
author | Canis, Martin Martin, Alexios Ihler, Friedrich Wolff, Hendrik A. Kron, Martina Matthias, Christoph Steiner, Wolfgang |
author_facet | Canis, Martin Martin, Alexios Ihler, Friedrich Wolff, Hendrik A. Kron, Martina Matthias, Christoph Steiner, Wolfgang |
author_sort | Canis, Martin |
collection | PubMed |
description | The objective of the study was to evaluate the oncological and functional results of transoral laser microsurgery (TLM) in patients with supraglottic laryngeal squamous cell carcinoma. Between June 1980 and December 2006, 277 patients with squamous cell supraglottic carcinoma of all stages were treated by primary carbon dioxide laser microsurgery. All treatments were performed with curative intention. The goal was the complete tumor removal with preservation of functionally important structures of the larynx. The administered treatment was exclusively TLM with or without selective or modified radical neck dissection in 215 cases (78 %); TLM with postoperative radiotherapy was performed in 62 cases (22 %). Data were analyzed using the Kaplan–Meier method. The median follow-up was 65 months. We achieved a 5-year local control rate of 85 % for pT1/pT2, 82 % for pT3, and 76 % for pT4. The 5-year overall, recurrence-free and disease-specific survival rates for stages I and II were 76, 81, and 92 %, for stages III and IVa 59, 65, and 81 %, respectively. With respect to local control and survival, these results are comparable with the results achieved by conventional partial and total resection of the larynx, while being superior to primary (chemo)radiotherapy. Transoral laser microsurgery results in a low morbidity, rapid recovery, and superior function compared with standard therapy. |
format | Online Article Text |
id | pubmed-3699705 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-36997052013-07-09 Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients Canis, Martin Martin, Alexios Ihler, Friedrich Wolff, Hendrik A. Kron, Martina Matthias, Christoph Steiner, Wolfgang Eur Arch Otorhinolaryngol Head and Neck The objective of the study was to evaluate the oncological and functional results of transoral laser microsurgery (TLM) in patients with supraglottic laryngeal squamous cell carcinoma. Between June 1980 and December 2006, 277 patients with squamous cell supraglottic carcinoma of all stages were treated by primary carbon dioxide laser microsurgery. All treatments were performed with curative intention. The goal was the complete tumor removal with preservation of functionally important structures of the larynx. The administered treatment was exclusively TLM with or without selective or modified radical neck dissection in 215 cases (78 %); TLM with postoperative radiotherapy was performed in 62 cases (22 %). Data were analyzed using the Kaplan–Meier method. The median follow-up was 65 months. We achieved a 5-year local control rate of 85 % for pT1/pT2, 82 % for pT3, and 76 % for pT4. The 5-year overall, recurrence-free and disease-specific survival rates for stages I and II were 76, 81, and 92 %, for stages III and IVa 59, 65, and 81 %, respectively. With respect to local control and survival, these results are comparable with the results achieved by conventional partial and total resection of the larynx, while being superior to primary (chemo)radiotherapy. Transoral laser microsurgery results in a low morbidity, rapid recovery, and superior function compared with standard therapy. Springer Berlin Heidelberg 2013-01-10 2013 /pmc/articles/PMC3699705/ /pubmed/23306348 http://dx.doi.org/10.1007/s00405-012-2327-6 Text en © The Author(s) 2013 https://creativecommons.org/licenses/by/2.0/ Open AccessThis article is distributed under the terms of the Creative Commons Attribution License which permits any use, distribution, and reproduction in any medium, provided the original author(s) and the source are credited. |
spellingShingle | Head and Neck Canis, Martin Martin, Alexios Ihler, Friedrich Wolff, Hendrik A. Kron, Martina Matthias, Christoph Steiner, Wolfgang Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients |
title | Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients |
title_full | Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients |
title_fullStr | Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients |
title_full_unstemmed | Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients |
title_short | Results of transoral laser microsurgery for supraglottic carcinoma in 277 patients |
title_sort | results of transoral laser microsurgery for supraglottic carcinoma in 277 patients |
topic | Head and Neck |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699705/ https://www.ncbi.nlm.nih.gov/pubmed/23306348 http://dx.doi.org/10.1007/s00405-012-2327-6 |
work_keys_str_mv | AT canismartin resultsoftransorallasermicrosurgeryforsupraglotticcarcinomain277patients AT martinalexios resultsoftransorallasermicrosurgeryforsupraglotticcarcinomain277patients AT ihlerfriedrich resultsoftransorallasermicrosurgeryforsupraglotticcarcinomain277patients AT wolffhendrika resultsoftransorallasermicrosurgeryforsupraglotticcarcinomain277patients AT kronmartina resultsoftransorallasermicrosurgeryforsupraglotticcarcinomain277patients AT matthiaschristoph resultsoftransorallasermicrosurgeryforsupraglotticcarcinomain277patients AT steinerwolfgang resultsoftransorallasermicrosurgeryforsupraglotticcarcinomain277patients |