Cargando…
Monitoring the Dynamics of T Cell Clonal Diversity Using Recombinant Peptide:MHC Technology
The capacity to probe antigen specific T cells within the polyclonal repertoire has been revolutionized by the advent of recombinant peptide:MHC (pMHC) technology. Monomers and multimers of pMHC molecules can enrich for and identify antigen specific T cells to elucidate the contributions of T cell f...
Autores principales: | Blanchfield, J. Lori, Shorter, Shayla K., Evavold, Brian D. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699728/ https://www.ncbi.nlm.nih.gov/pubmed/23840195 http://dx.doi.org/10.3389/fimmu.2013.00170 |
Ejemplares similares
-
Trans-Allelic Model for Prediction of Peptide:MHC-II Interactions
por: Degoot, Abdoelnaser M., et al.
Publicado: (2018) -
Computationally profiling peptide:MHC recognition by T-cell receptors and T-cell receptor-mimetic antibodies
por: Raybould, Matthew I. J., et al.
Publicado: (2023) -
Derivation of an amino acid similarity matrix for peptide:MHC binding and its application as a Bayesian prior
por: Kim, Yohan, et al.
Publicado: (2009) -
Dynamically Driven Allostery in MHC Proteins: Peptide-Dependent Tuning of Class I MHC Global Flexibility
por: Ayres, Cory M., et al.
Publicado: (2019) -
Proofreading of Peptide—MHC Complexes through Dynamic Multivalent Interactions
por: Thomas, Christoph, et al.
Publicado: (2017)