Synergistic Effect of Subtoxic-dose Cisplatin and TRAIL to Mediate Apoptosis by Down-regulating Decoy Receptor 2 and Up-regulating Caspase-8, Caspase-9 and Bax Expression on NCI-H460 and A549 Cells

Objective(s) : Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis in tumor cells, more than half of tumors including non-small cell lung cancer (NSCLC) exhibit TRAIL-resistance. The purpose of this study was to determine whether subtoxic-dose ci...

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Detalles Bibliográficos
Autores principales: Zhang, Xiaoyan, Zhao, Jing, Zhu, Wenyan, Gou, Hongfeng, Cao, Dan, Yang, Yu, Huang, Ying, Yi, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mashhad University of Medical Sciences 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700047/
https://www.ncbi.nlm.nih.gov/pubmed/23826494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700047/
https://www.ncbi.nlm.nih.gov/pubmed/23826494

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