Cargando…

Synthesis and Biological Activity of New Thiopyrano[2,3-d]thiazoles Containing a Naphthoquinone Moiety

Novel 11-substituted 3,11-dihydro-2H-benzo[6,7]thiochromeno[2,3-d][1,3]-thiazole-2,5,10-triones 4a–i were synthesized in 75–90% yields via the hetero-Diels-Alder reaction of 5-arylidene-4-thioxo-2-thiazolidinones with 1,4-naphthoquinone. The synthesized compounds were evaluated for their antineoplas...

Descripción completa

Detalles Bibliográficos
Autores principales:	Atamanyuk, Dmytro, Zimenkovsky, Borys, Atamanyuk, Vasyl, Nektegayev, Ihor, Lesyk, Roman
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700073/ https://www.ncbi.nlm.nih.gov/pubmed/23833711 http://dx.doi.org/10.3797/scipharm.1301-13

Ejemplares similares

Fused Thiopyrano[2,3-d]thiazole Derivatives as Potential Anticancer Agents
por: Kryshchyshyn, Anna, et al.
Publicado: (2012)

Synthesis and Anticancer Activity of New Thiopyrano[2,3-d]thiazoles Based on Cinnamic Acid Amides
por: Lozynskyi, Andrii, et al.
Publicado: (2014)

1,4-Naphthoquinone Motif in the Synthesis of New Thiopyrano[2,3-d]thiazoles as Potential Biologically Active Compounds
por: Lozynskyi, Andrii, et al.
Publicado: (2022)

Thiopyrano[2,3-d]Thiazoles as New Efficient Scaffolds in Medicinal Chemistry
por: Kryshchyshyn, Anna, et al.
Publicado: (2018)

2-[7-(3,5-Dibromo-2-hydroxyphenyl)-6-ethoxycarbonyl-2-oxo-5H-2,3,6,7-tetrahydrothiopyrano[2,3-d][1,3]thiazol-6-yl]acetic acid ethanol monosolvate
por: Kowiel, M., et al.
Publicado: (2012)

Synthesis and biological activity evaluation of 5-pyrazoline substituted 4-thiazolidinones
por: Havrylyuk, Dmytro, et al.
Publicado: (2013)

Novel Thiopyrano[2,3-d]thiazole-pyrazole Hybrids as Potential Nonsulfonamide Human Carbonic Anhydrase IX and XII Inhibitors: Design, Synthesis, and Biochemical Studies
por: Metwally, Nadia Hanafy, et al.
Publicado: (2023)

Development of Novel Pyridine-Thiazole Hybrid Molecules as Potential Anticancer Agents
por: Ivasechko, Iryna, et al.
Publicado: (2022)

Eco-Friendly Synthesis, Characterization and Biological Evaluation of Some Novel Pyrazolines Containing Thiazole Moiety as Potential Anticancer and Antimicrobial Agents
por: Edrees, Mastoura M., et al.
Publicado: (2018)

Synthesis and Anticancer Evaluation of New Thiazole and Thiadiazole Derivatives Bearing Acetanilide Moiety
por: El-Rayyes, Ali, et al.
Publicado: (2022)

Computational method of the cardiovascular diseases classification based on a generalized nonlinear canonical decomposition of random sequences
por: Atamanyuk, Igor, et al.
Publicado: (2023)

4-Thiazolidinone derivative Les-3833 effectively inhibits viability of human melanoma cells through activating apoptotic mechanisms
por: Finiuk, Nataliya, et al.
Publicado: (2017)

Synthesis of Some New 1,3,4-Thiadiazole, Thiazole and Pyridine Derivatives Containing 1,2,3-Triazole Moiety
por: Abdelriheem, Nadia A., et al.
Publicado: (2017)

A synergistic investigation of azo-thiazole derivatives incorporating thiazole moieties: a comprehensive exploration of their synthesis, characterization, computational insights, solvatochromism, and multimodal biological activity assessment
por: Muhammed Aziz, Dara, et al.
Publicado: (2023)

Potential COVID-19 Drug Candidates Based on Diazinyl-Thiazol-Imine Moieties: Synthesis and Greener Pastures Biological Study
por: Abu-Melha, Sraa, et al.
Publicado: (2022)

Synthesis and antimicrobial activity of new series of thiazoles, pyridines and pyrazoles based on coumarin moiety
por: Sayed, Mariam T., et al.
Publicado: (2023)

Copper Complexes of 1,4-Naphthoquinone Containing Thiosemicarbazide and Triphenylphosphine Oxide Moieties; Synthesis and Identification by NMR, IR, Mass, UV Spectra, and DFT Calculations
por: Alshammari, Mohammed B., et al.
Publicado: (2022)

Zinc-Catalyzed Enantioselective [3 + 3] Annulation for Synthesis of Chiral Spiro[indoline-3,4′-thiopyrano[2,3-b]indole] Derivatives
por: Liu, Tian-Tian, et al.
Publicado: (2023)

Thiazole: A Versatile Standalone Moiety Contributing to the Development of Various Drugs and Biologically Active Agents
por: Arshad, Mohammed F., et al.
Publicado: (2022)

Machine Learning Techniques for Increasing Efficiency of the Robot’s Sensor and Control Information Processing †
por: Kondratenko, Yuriy, et al.
Publicado: (2022)

Design, synthesis and biological activities of echinopsine derivatives containing acylhydrazone moiety
por: Cui, Peipei, et al.
Publicado: (2022)

Synthesis and Antimicrobial Studies of Some Novel Bis-[1,3,4]thiadiazole and Bis-thiazole Pendant to Thieno[2,3-b]thiophene Moiety
por: Kheder, Nabila Abdelshafy, et al.
Publicado: (2012)

Synthesis and Antimicrobial Evaluation of Some Novel Thiazole, Pyridone, Pyrazole, Chromene, Hydrazone Derivatives Bearing a Biologically Active Sulfonamide Moiety
por: Darwish, Elham S., et al.
Publicado: (2014)

Design, synthesis and docking studies of novel thiazole derivatives incorporating pyridine moiety and assessment as antimicrobial agents
por: Khidre, Rizk E., et al.
Publicado: (2021)

2-[N-(4-Methoxyphenyl)acetamido]-1,3-thiazol-4-yl acetate
por: Horishny, Volodymyr, et al.
Publicado: (2013)

SYNTHESIS AND BIOLOGICAL ACTIVITIES OF CERTAIN MESOIONIC SYDNONE COMPOUNDS CONTAINING CHALCONE MOIETY
por: Deshpande, Shreenivas R., et al.
Publicado: (2010)

Synthesis and biological activities of novel trifluoromethylpyridine amide derivatives containing sulfur moieties
por: Guo, S. X., et al.
Publicado: (2020)

Naphthoquinone amino acid derivatives, synthesis and biological activity as proteasome inhibitors
por: Marastoni, Mauro, et al.
Publicado: (2017)

Synthetic approaches, structure activity relationship and biological applications for pharmacologically attractive pyrazole/pyrazoline–thiazolidine-based hybrids
por: Havrylyuk, Dmytro, et al.
Publicado: (2016)

Synthesis and Characterization of Some New Bis-Pyrazolyl-Thiazoles Incorporating the Thiophene Moiety as Potent Anti-Tumor Agents
por: Gomha, Sobhi M., et al.
Publicado: (2016)

A facile synthesis and anticancer activity of some novel thiazoles carrying 1,3,4-thiadiazole moiety
por: Gomha, Sobhi M., et al.
Publicado: (2017)

Synthesis and potential antimicrobial activity of novel α-aminophosphonates derivatives bearing substituted quinoline or quinolone and thiazole moieties
por: Litim, Bilal, et al.
Publicado: (2021)

Novel 1,2,4-Triazole- and Tetrazole-Containing 4H-Thiopyrano[2,3-b]quinolines: Synthesis Based on the Thio-Michael/aza-Morita–Baylis–Hillman Tandem Reaction and Investigation of Antiviral Activity
por: Khramchikhin, Andrey V., et al.
Publicado: (2023)

Synthesis and Biological Investigation of some Novel Sulfonamide and Amide Derivatives Containing Coumarin Moieties
por: Saeedi, Mina, et al.
Publicado: (2014)

Molecular Docking Study for Binding Affinity of 2H-thiopyrano[2,3-b]quinoline Derivatives against CB1a
por: Sharma, Shivangi, et al.
Publicado: (2023)

2-[N-(2,4-Dimethoxyphenyl)acetamido]-1,3-thiazol-4-yl acetate
por: Horishny, Volodymyr, et al.
Publicado: (2013)

Synthesis of kinase inhibitors containing a pentafluorosulfanyl moiety
por: Sansook, Supojjanee, et al.
Publicado: (2017)

Surgical treatment of bicuspid aortic valve disease
por: Kravchenko, Ivan, et al.
Publicado: (2013)

Synthesis and Biological Evaluation of Novel Hybrid Molecules Containing Purine, Coumarin and Isoxazoline or Isoxazole Moieties
por: Kallitsakis, Michael G., et al.
Publicado: (2017)

Synthesis and Biological Evaluation of 3-Substituted-indolin-2-one Derivatives Containing Chloropyrrole Moieties
por: Jin, Yun-Zhou, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_0vqdi293s3abkjokrrd09l2mfk