Cargando…

Determination of Cefixime by a Validated Stability-Indicating HPLC Method and Identification of its Related Substances by LC-MS/MS Studies

Cefixime is an important cephalosporin antibiotic that easily decomposes and releases different related substances in preparation and storage steps. The objective of the current study was to develop a simple, precise, and accurate isocratic liquid chromatography (LC) method for the determination of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Talebpour, Zahra, Pourabdollahi, Hakimeh, Rafati, Hasan, Abdollahpour, Asem, Bashour, Yusef, Aboul-Enein, Hassan Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Österreichische Apotheker-Verlagsgesellschaft 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700077/ https://www.ncbi.nlm.nih.gov/pubmed/23833715 http://dx.doi.org/10.3797/scipharm.1301-15

Ejemplares similares

A conventional HPLC-MS method for the simultaneous determination of ofloxacin and cefixime in plasma: Development and validation
por: Attimarad, Mahesh V., et al.
Publicado: (2013)

Quick and Sensitive UPLC-ESI-MS/MS Method for Simultaneous Estimation of Sofosbuvir and Its Metabolite in Human Plasma
por: Semreen, Mohammad H., et al.
Publicado: (2019)

Development and Validation of Stability-indicating HPLC Method for Simultaneous Estimation of Cefixime and Linezolid
por: Patel, Nidhi S., et al.
Publicado: (2014)

Study of forced degradation behavior of pramlintide acetate by HPLC and LC–MS
por: Yuan, Yu, et al.
Publicado: (2017)

Development Rapid Analytical Methods for Inositol as a Trace Component by HPLC and LC-MS/MS in Infant Formula
por: Shin, Jin-Ho, et al.
Publicado: (2015)

LC, MS(n) and LC–MS/MS studies for the characterization of degradation products of amlodipine
por: Tiwari, Ravi N., et al.
Publicado: (2015)

Identification and Quantification of 29 Active Substances by HPLC–ESI-MS/MS in Lyophilized Swine Manure Samples
por: Nebot, Carolina, et al.
Publicado: (2022)

Study of Degradation Kinetics and Structural Analysis of Related Substances of Ceftobiprole by HPLC with UV and MS/MS Detection
por: Boczar, Dariusz, et al.
Publicado: (2022)

Optimization of Microwave-Assisted Extraction for the Determination of Glycyrrhizin in Menthazin Herbal Drug by Experimental Design Methodology
por: Talebpour, Zahra, et al.
Publicado: (2009)

Fecal metabolite analysis of Japanese macaques in Yakushima by LC-MS/MS and LC-QTOF-MS
por: TSUCHIDA, Sayaka, et al.
Publicado: (2021)

Chemical Profiling of an Antimigraine Herbal Preparation, Tianshu Capsule, Based on the Combination of HPLC, LC-DAD-MS(n), and LC-DAD-ESI-IT-TOF/MS Analyses
por: Liang, Juanjuan, et al.
Publicado: (2014)

Fast Quantitative LC-MS/MS Determination of Illicit Substances in Solid and Liquid Unknown Seized Samples
por: Merone, Giuseppe M., et al.
Publicado: (2021)

Determination of Oseltamivir in Human Plasma by HPLC-MS/MS
por: Lakeev, A. P., et al.
Publicado: (2023)

Largazole Pharmacokinetics in Rats by LC-MS/MS
por: Yu, Mingming, et al.
Publicado: (2014)

Application of LC–MS/MS in the Mycotoxins Studies
por: Gámiz-Gracia, Laura, et al.
Publicado: (2020)

Phase II Metabolism of Asarone Isomers In Vitro and in Humans Using HPLC-MS/MS and HPLC-qToF/MS
por: Hermes, Lena, et al.
Publicado: (2021)

Quantification for non-targeted LC/MS screening without standard substances
por: Liigand, Jaanus, et al.
Publicado: (2020)

Comparison of Flow Injection-MS/MS and LC-MS/MS for the Determination of Ochratoxin A
por: Zhang, Kai
Publicado: (2021)

One-step extraction and determination of 513 psychoactive substances, drugs, and their metabolites from hair by LC–MS/MS
por: Musiał, Jadwiga, et al.
Publicado: (2022)

LC and LC–MS/MS studies for the identification and characterization of degradation products of acebutolol
por: Rakibe, Uday, et al.
Publicado: (2018)

Determination of Reduced and Oxidized Coenzyme Q(10) in Canine Plasma and Heart Tissue by HPLC-ECD: Comparison with LC-MS/MS Quantification
por: Schou-Pedersen, Anne Marie V., et al.
Publicado: (2019)

Kinetics and Characterization of Degradation Products of Dihydralazine and Hydrochlorothiazide in Binary Mixture by HPLC-UV, LC-DAD and LC–MS Methods
por: Gumieniczek, Anna, et al.
Publicado: (2018)

HPLC-ESI-MS/MS of Imidazole Alkaloids in Pilocarpus microphyllus
por: Sawaya, Alexandra CH F, et al.
Publicado: (2008)

Development of an HPLC-MS/MS Method for the Determination of Alkaloids in Lupins
por: Eugelio, Fabiola, et al.
Publicado: (2023)

Simultaneous Identification and Quantification of Canrenone and 11-α-Hydroxy-Canrenone by LC-MS and HPLC-UVD
por: Huang, Da-Ming, et al.
Publicado: (2011)

Comparative Analysis of the Bufonis Venenum by Using TLC, HPLC, and LC-MS for Different Extraction Methods
por: Lee, Hyo-Jae, et al.
Publicado: (2012)

Evaluation of LC-MS and LC×LC-MS in analysis of zebrafish embryo samples for comprehensive lipid profiling
por: Xu, Mengmeng, et al.
Publicado: (2020)

Integrated LC-MS/MS system for plant metabolomics
por: Sawada, Yuji, et al.
Publicado: (2013)

Qualitative and quantitative assessment of related substances in the Compound Ketoconazole and Clobetasol Propionate Cream by HPLC-TOF-MS and HPLC
por: Yang, Wenling, et al.
Publicado: (2019)

Determination of Nine Fentanyl Drugs in Hair Samples by GC-MS/MS and LC-MS/MS
por: Wei, Qi, et al.
Publicado: (2022)

Determination of 355 Pesticides in Lemon and Lemon Juice by LC-MS/MS and GC-MS/MS
por: Aslantas, Sule, et al.
Publicado: (2023)

Pigments’ analysis of Citrus juicing making by‐products by LC‐MS/MS and LC‐DAD
por: Myrtsi, Eleni D., et al.
Publicado: (2022)

Fast and high-throughput LC-MS characterization, and peptide mapping of engineered AAV capsids using LC-MS/MS
por: Lam, Anh K., et al.
Publicado: (2022)

HPLC MS-MS Analysis Shows Measurement of Corticosterone in Egg Albumen Is Not a Valid Indicator of Chicken Welfare
por: Caulfield, Malcolm P., et al.
Publicado: (2020)

Intracellular Accumulation as an Indicator of Cytotoxicity to Screen Hepatotoxic Components of Chelidonium majus L. by LC–MS/MS
por: Wu, Cuiting, et al.
Publicado: (2019)

Development and validation of a rapid LC‐MS/MS method for the detection of 182 novel psychoactive substances in whole blood
por: Giorgetti, Arianna, et al.
Publicado: (2021)

Quality assessment of traditional herbal formula, Hyeonggaeyeongyo-tang through simultaneous determination of twenty marker components by HPLC–PDA and LC–MS/MS
por: Seo, Chang-Seob, et al.
Publicado: (2020)

Identification and characterization of related substances in EVT-401 by hyphenated LC–MS techniques
por: Zhu, Binan, et al.
Publicado: (2017)

Green Extraction of Alkaloids and Polyphenols from Peumus boldus Leaves with Natural Deep Eutectic Solvents and Profiling by HPLC-PDA-IT-MS/MS and HPLC-QTOF-MS/MS
por: Torres-Vega, Jeniffer, et al.
Publicado: (2020)

Comprehensive Quality Assessment of Kaixin Powder by HPLC–DAD Quantification and HPLC–QTOF-MS/MS Confirmation
por: Wang, Binbin, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_acms5o48hk4gqm8ipdb4djn1id