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COORDINATED ACTIVATION OF THE RAC-GAP β2-CHIMAERIN BY AN ATYPICAL PROLINE-RICH DOMAIN AND DIACYLGLYCEROL

Chimaerins, a family of GTPase activating proteins (GAPs) for the small G-protein Rac, have been implicated in development, neuritogenesis, and cancer. These Rac-GAPs are regulated by the lipid second messenger diacylglycerol (DAG) generated by tyrosine-kinases such as the epidermal growth factor re...

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Detalles Bibliográficos
Autores principales:	Gutierrez-Uzquiza, Alvaro, Colon-Gonzalez, Francheska, Leonard, Thomas A., Canagarajah, Bertram J., Wang, HongBin, Mayer, Bruce J., Hurley, James H., Kazanietz, Marcelo G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700536/ https://www.ncbi.nlm.nih.gov/pubmed/23673634 http://dx.doi.org/10.1038/ncomms2834

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