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Structure of the Chemokine Receptor CXCR1 in Phospholipid Bilayers

CXCR1 is one of two high-affinity receptors for the CXC chemokine interleukin-8 (IL-8), a major mediator of immune and inflammatory responses implicated in many disorders, including tumor growth(1-3). IL-8, released in response to inflammatory stimuli, binds to the extracellular side of CXCR1. The l...

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Detalles Bibliográficos
Autores principales: Park, Sang Ho, Das, Bibhuti B., Casagrande, Fabio, Tian, Ye, Nothnagel, Henry J., Chu, Mignon, Kiefer, Hans, Maier, Klaus, De Angelis, Anna, Marassi, Francesca M., Opella, Stanley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700570/
https://www.ncbi.nlm.nih.gov/pubmed/23086146
http://dx.doi.org/10.1038/nature11580