Migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study”

We discuss the hypothesis proposed by Engstrom and coworkers that Migraineurs have a relative sleep deprivation, which lowers the pain threshold and predispose to attacks. Previous data indicate that Migraineurs have a reduction of Cyclic Alternating Pattern (CAP), an essential mechanism of NREM sle...

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Autores principales: Vollono, Catello, Testani, Elisa, Losurdo, Anna, Mazza, Salvatore, Marca, Giacomo Della
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2013
Materias:
Letter to the Editor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700761/
https://www.ncbi.nlm.nih.gov/pubmed/23758606
http://dx.doi.org/10.1186/1129-2377-14-50
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author Vollono, Catello
Testani, Elisa
Losurdo, Anna
Mazza, Salvatore
Marca, Giacomo Della
author_facet Vollono, Catello
Testani, Elisa
Losurdo, Anna
Mazza, Salvatore
Marca, Giacomo Della
author_sort Vollono, Catello
collection PubMed
description We discuss the hypothesis proposed by Engstrom and coworkers that Migraineurs have a relative sleep deprivation, which lowers the pain threshold and predispose to attacks. Previous data indicate that Migraineurs have a reduction of Cyclic Alternating Pattern (CAP), an essential mechanism of NREM sleep regulation which allows to dump the effect of incoming disruptive stimuli, and to protect sleep. The modifications of CAP observed in Migraineurs are similar to those observed in patients with impaired arousal (narcolepsy) and after sleep deprivation. The impairment of this mechanism makes Migraineurs more vulnerable to stimuli triggering attacks during sleep, and represents part of a more general vulnerability to incoming stimuli.
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spelling pubmed-37007612013-07-08 Migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study” Vollono, Catello Testani, Elisa Losurdo, Anna Mazza, Salvatore Marca, Giacomo Della J Headache Pain Letter to the Editor We discuss the hypothesis proposed by Engstrom and coworkers that Migraineurs have a relative sleep deprivation, which lowers the pain threshold and predispose to attacks. Previous data indicate that Migraineurs have a reduction of Cyclic Alternating Pattern (CAP), an essential mechanism of NREM sleep regulation which allows to dump the effect of incoming disruptive stimuli, and to protect sleep. The modifications of CAP observed in Migraineurs are similar to those observed in patients with impaired arousal (narcolepsy) and after sleep deprivation. The impairment of this mechanism makes Migraineurs more vulnerable to stimuli triggering attacks during sleep, and represents part of a more general vulnerability to incoming stimuli. Springer 2013 2013-06-10 /pmc/articles/PMC3700761/ /pubmed/23758606 http://dx.doi.org/10.1186/1129-2377-14-50 Text en Copyright ©2013 Vollono et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Letter to the Editor
Vollono, Catello
Testani, Elisa
Losurdo, Anna
Mazza, Salvatore
Marca, Giacomo Della
Migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study”
title Migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study”
title_full Migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study”
title_fullStr Migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study”
title_full_unstemmed Migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study”
title_short Migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study”
title_sort migraine, arousal and sleep deprivation: comment on: “sleep quality, arousal and pain thresholds in migraineurs: a blinded controlled polysomnographic study”
topic Letter to the Editor
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700761/
https://www.ncbi.nlm.nih.gov/pubmed/23758606
http://dx.doi.org/10.1186/1129-2377-14-50
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