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Anti-Aggregating Effect of the Naturally Occurring Dipeptide Carnosine on Aβ1-42 Fibril Formation
Carnosine is an endogenous dipeptide abundant in the central nervous system, where by acting as intracellular pH buffering molecule, Zn/Cu ion chelator, antioxidant and anti-crosslinking agent, it exerts a well-recognized multi-protective homeostatic function for neuronal and non-neuronal cells. Car...
Autores principales: | Aloisi, Alessandra, Barca, Amilcare, Romano, Alessandro, Guerrieri, Sara, Storelli, Carlo, Rinaldi, Rosaria, Verri, Tiziano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700870/ https://www.ncbi.nlm.nih.gov/pubmed/23844165 http://dx.doi.org/10.1371/journal.pone.0068159 |
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