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BRCA2 affects the efficiency of DNA double-strand break repair in response to N-nitroso compounds with differing carcinogenic potentials

The tumor suppressor gene breast cancer susceptibility gene 2 (BRCA2) is frequently mutated or epigenetically repressed in human cancer and has a significant role in the homologous recombination (HR) of DNA double-strand breaks (DSBs). Although N-nitrosodiethylamine (NDEA), N-nitrosodiethanolamine (...

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Detalles Bibliográficos
Autores principales:	ZHAO, WEN-TING, WANG, YU-TIAN, HUANG, ZHAO-WEI, FANG, JING
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700919/ https://www.ncbi.nlm.nih.gov/pubmed/23833673 http://dx.doi.org/10.3892/ol.2013.1269

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