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Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis
We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during e...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Libertas Academica
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700939/ https://www.ncbi.nlm.nih.gov/pubmed/23843718 http://dx.doi.org/10.4137/CCRep.S11890 |
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author | Matsuzono, Kosuke Kurata, Tomoko Deguchi, Shoko Yamashita, Toru Deguchi, Kentaro Ikeda, Yoshio Abe, Koji |
author_facet | Matsuzono, Kosuke Kurata, Tomoko Deguchi, Shoko Yamashita, Toru Deguchi, Kentaro Ikeda, Yoshio Abe, Koji |
author_sort | Matsuzono, Kosuke |
collection | PubMed |
description | We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during early stages, the present cases showed MRI lesions during later stages in the bilateral claustrum and pons. In both cases, anti-GluRɛ2 and δ2 antibodies were later shown to be positive in the cerebrospinal fluid but negative in the serum. Although early detection of anti-GluR antibodies is essential, early treatment may be significantly more important. |
format | Online Article Text |
id | pubmed-3700939 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Libertas Academica |
record_format | MEDLINE/PubMed |
spelling | pubmed-37009392013-07-10 Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis Matsuzono, Kosuke Kurata, Tomoko Deguchi, Shoko Yamashita, Toru Deguchi, Kentaro Ikeda, Yoshio Abe, Koji Clin Med Insights Case Rep Case Report We report two cases of anti-glutamic acid receptor (anti-GluR) antibody-positive encephalitis in males with symptoms such as Parkinsonism, urinary retention, and paralytic ileus. Although non-herpetic encephalitis typically shows magnetic resonance imaging (MRI) lesions in the limbic system during early stages, the present cases showed MRI lesions during later stages in the bilateral claustrum and pons. In both cases, anti-GluRɛ2 and δ2 antibodies were later shown to be positive in the cerebrospinal fluid but negative in the serum. Although early detection of anti-GluR antibodies is essential, early treatment may be significantly more important. Libertas Academica 2013-06-23 /pmc/articles/PMC3700939/ /pubmed/23843718 http://dx.doi.org/10.4137/CCRep.S11890 Text en © 2013 the author(s), publisher and licensee Libertas Academica Ltd. This is an open access article published under the Creative Commons CC-BY-NC 3.0 license. |
spellingShingle | Case Report Matsuzono, Kosuke Kurata, Tomoko Deguchi, Shoko Yamashita, Toru Deguchi, Kentaro Ikeda, Yoshio Abe, Koji Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis |
title | Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis |
title_full | Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis |
title_fullStr | Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis |
title_full_unstemmed | Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis |
title_short | Two Unique Cases with Anti-GluR Antibody-Positive Encephalitis |
title_sort | two unique cases with anti-glur antibody-positive encephalitis |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700939/ https://www.ncbi.nlm.nih.gov/pubmed/23843718 http://dx.doi.org/10.4137/CCRep.S11890 |
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