Systemic Inhibition of Canonical Notch Signaling Results in Sustained Callus Inflammation and Alters Multiple Phases of Fracture Healing

The Notch signaling pathway is an important regulator of embryological bone development, and many aspects of development are recapitulated during bone repair. We have previously reported that Notch signaling components are upregulated during bone fracture healing. However, the significance of the No...

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Detalles Bibliográficos
Autores principales: Dishowitz, Michael I., Mutyaba, Patricia L., Takacs, Joel D., Barr, Andrew M., Engiles, Julie B., Ahn, Jaimo, Hankenson, Kurt D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701065/
https://www.ncbi.nlm.nih.gov/pubmed/23844237
http://dx.doi.org/10.1371/journal.pone.0068726

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