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An integrin-ILK-microtubule network orients cell polarity and lumen formation in glandular epithelium
The extracellular matrix has a crucial role in determining the spatial orientation of epithelial polarity and the formation of lumens in glandular tissues, however the underlying mechanisms remain elusive. By using Cre-Lox deletion we show that β1-integrins are required for normal mammary gland morp...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701152/ https://www.ncbi.nlm.nih.gov/pubmed/23263281 http://dx.doi.org/10.1038/ncb2646 |