Cargando…
Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology
BACKGROUND: Pancreatic and peripancreatic tuberculosis is an extremely uncommon disease, presenting as hypoechoic mass on ultrasonography and imaging mimicking malignancy. Consequently, it represents a diagnostic challenge. AIMS: To study 14 unusual cases of pancreatic and peripancreatic tuberculosi...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701338/ https://www.ncbi.nlm.nih.gov/pubmed/23833404 http://dx.doi.org/10.4103/0970-9371.112658 |
_version_ | 1782275621968150528 |
---|---|
author | Rao, R. N. Pandey, Rakesh Rana, Manoj Kumar Rai, Praveer Gupta, Archna |
author_facet | Rao, R. N. Pandey, Rakesh Rana, Manoj Kumar Rai, Praveer Gupta, Archna |
author_sort | Rao, R. N. |
collection | PubMed |
description | BACKGROUND: Pancreatic and peripancreatic tuberculosis is an extremely uncommon disease, presenting as hypoechoic mass on ultrasonography and imaging mimicking malignancy. Consequently, it represents a diagnostic challenge. AIMS: To study 14 unusual cases of pancreatic and peripancreatic tuberculosis undergoing ultrasound-/endoscopic-guided fine-needle aspiration cytology (FNAC) in the 5-year period from 2006 to 2010. MATERIALS AND METHODS: Endoscopic-guided FNAC was done in two cases, while ultrasound-guided FNAC was performed in 12 cases using 22-G needles via a percutaneous transabdominal approach. The aspirated material was quickly smeared onto glass slides, air dried, and wet fixed in 95% ethyl alcohol for subsequent Papanicolaou staining. RESULTS: All pancreatic and peripancreatic tuberculosis cases showed solid-cystic pancreatic mass. Smears showed epithelioid cell granulomas, multinucleated giant cells, mixed inflammatory cells and histiocytes against a necrotic background. The common anatomic locations were the head, peripancreatic, tail and body of the pancreas. CONCLUSIONS: Ultrasound-/endoscopic-guided FNAC is a safe, reliable and cost-effective method for preoperative diagnosis of pancreatic and peripancreatic tuberculosis. Clinical symptoms and accurate diagnostic approach by ultrasound-/endoscopic-guided FNAC of pancreatic and peripancreatic tuberculosis is needed to avoid performing redundant laparotomy. Despite its rarity, pancreatic and peripancreatic tuberculosis should be considered for differential diagnosis of pancreatic and peripancreatic cystic mass in endemic developing countries. |
format | Online Article Text |
id | pubmed-3701338 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-37013382013-07-05 Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology Rao, R. N. Pandey, Rakesh Rana, Manoj Kumar Rai, Praveer Gupta, Archna J Cytol Original Article BACKGROUND: Pancreatic and peripancreatic tuberculosis is an extremely uncommon disease, presenting as hypoechoic mass on ultrasonography and imaging mimicking malignancy. Consequently, it represents a diagnostic challenge. AIMS: To study 14 unusual cases of pancreatic and peripancreatic tuberculosis undergoing ultrasound-/endoscopic-guided fine-needle aspiration cytology (FNAC) in the 5-year period from 2006 to 2010. MATERIALS AND METHODS: Endoscopic-guided FNAC was done in two cases, while ultrasound-guided FNAC was performed in 12 cases using 22-G needles via a percutaneous transabdominal approach. The aspirated material was quickly smeared onto glass slides, air dried, and wet fixed in 95% ethyl alcohol for subsequent Papanicolaou staining. RESULTS: All pancreatic and peripancreatic tuberculosis cases showed solid-cystic pancreatic mass. Smears showed epithelioid cell granulomas, multinucleated giant cells, mixed inflammatory cells and histiocytes against a necrotic background. The common anatomic locations were the head, peripancreatic, tail and body of the pancreas. CONCLUSIONS: Ultrasound-/endoscopic-guided FNAC is a safe, reliable and cost-effective method for preoperative diagnosis of pancreatic and peripancreatic tuberculosis. Clinical symptoms and accurate diagnostic approach by ultrasound-/endoscopic-guided FNAC of pancreatic and peripancreatic tuberculosis is needed to avoid performing redundant laparotomy. Despite its rarity, pancreatic and peripancreatic tuberculosis should be considered for differential diagnosis of pancreatic and peripancreatic cystic mass in endemic developing countries. Medknow Publications & Media Pvt Ltd 2013 /pmc/articles/PMC3701338/ /pubmed/23833404 http://dx.doi.org/10.4103/0970-9371.112658 Text en Copyright: © Journal of Cytology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Rao, R. N. Pandey, Rakesh Rana, Manoj Kumar Rai, Praveer Gupta, Archna Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology |
title | Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology |
title_full | Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology |
title_fullStr | Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology |
title_full_unstemmed | Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology |
title_short | Pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology |
title_sort | pancreatic and peripancreatic tuberculosis presenting as hypoechoic mass and malignancy diagnosed by ultrasound-guided fine-needle aspiration cytology |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701338/ https://www.ncbi.nlm.nih.gov/pubmed/23833404 http://dx.doi.org/10.4103/0970-9371.112658 |
work_keys_str_mv | AT raorn pancreaticandperipancreatictuberculosispresentingashypoechoicmassandmalignancydiagnosedbyultrasoundguidedfineneedleaspirationcytology AT pandeyrakesh pancreaticandperipancreatictuberculosispresentingashypoechoicmassandmalignancydiagnosedbyultrasoundguidedfineneedleaspirationcytology AT ranamanojkumar pancreaticandperipancreatictuberculosispresentingashypoechoicmassandmalignancydiagnosedbyultrasoundguidedfineneedleaspirationcytology AT raipraveer pancreaticandperipancreatictuberculosispresentingashypoechoicmassandmalignancydiagnosedbyultrasoundguidedfineneedleaspirationcytology AT guptaarchna pancreaticandperipancreatictuberculosispresentingashypoechoicmassandmalignancydiagnosedbyultrasoundguidedfineneedleaspirationcytology |