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Mild and efficient cyanuric chloride catalyzed Pictet–Spengler reaction

A practical, mild and efficient protocol for the Pictet–Spengler reaction catalyzed by cyanuric chloride (trichloro-1,3,5-triazine, TCT) is described. The 6-endo cyclization of tryptophan/tryptamine and modified Pictet–Spengler substrates with both electron-withdrawing and electron-donating aldehyde...

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Detalles Bibliográficos
Autores principales: Sharma, Ashish, Singh, Mrityunjay, Rai, Nitya Nand, Sawant, Devesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701375/
https://www.ncbi.nlm.nih.gov/pubmed/23843919
http://dx.doi.org/10.3762/bjoc.9.140