HES1, a target of Notch signaling, is elevated in canine osteosarcoma, but reduced in the most aggressive tumors

BACKGROUND: Hairy and enhancer of split 1 (HES1), a basic helix-loop-helix transcriptional repressor, is a downstream target of Notch signaling. Notch signaling and HES1 expression have been linked to growth and survival in a variety of human cancer types and have been associated with increased meta...

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Detalles Bibliográficos
Autores principales: Dailey, Deanna D, Anfinsen, Kristin P, Pfaff, Liza E, Ehrhart, EJ, Charles, J Brad, Bønsdorff, Tina B, Thamm, Douglas H, Powers, Barbara E, Jonasdottir, Thora J, Duval, Dawn L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701487/
https://www.ncbi.nlm.nih.gov/pubmed/23816051
http://dx.doi.org/10.1186/1746-6148-9-130

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