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Drosophila GAGA factor polyglutamine domains exhibit prion-like behavior

BACKGROUND: The Drosophila GAGA factor (GAF) participates in nucleosome remodeling to activate genes, acts as an antirepressor and is associated with heterochromatin, contributing to gene repression. GAF functions are intimately associated to chromatin-based epigenetic control, linking basic transcr...

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Detalles Bibliográficos
Autores principales: Tariq, Muhammad, Wegrzyn, Renee, Anwar, Saima, Bukau, Bernd, Paro, Renato
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701498/
https://www.ncbi.nlm.nih.gov/pubmed/23731888
http://dx.doi.org/10.1186/1471-2164-14-374

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