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Prothrombin complex concentrate in the reduction of blood loss during orthotopic liver transplantation: PROTON-trial

BACKGROUND: In patients with cirrhosis, the synthesis of coagulation factors can fall short, reflected by a prolonged prothrombin time. Although anticoagulants factors are decreased as well, blood loss during orthotopic liver transplantation can still be excessive. Blood loss during orthotopic liver...

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Detalles Bibliográficos
Autores principales: Arshad, Freeha, Ickx, Brigitte, van Beem, Rachel T, Polak, Wojciech, Grüne, Frank, Nevens, Frederik, Ilmakunnas, Minna, Koivusalo, Anna-Maria, Isoniemi, Helena, Strengers, Paul FW, Groen, Henk, Hendriks, Herman GD, Lisman, Ton, Pirenne, Jacques, Porte, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701501/
https://www.ncbi.nlm.nih.gov/pubmed/23815798
http://dx.doi.org/10.1186/1471-2482-13-22