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Tanshinone IIA Increases the Bystander Effect of Herpes Simplex Virus Thymidine Kinase/Ganciclovir Gene Therapy via Enhanced Gap Junctional Intercellular Communication

The bystander effect is an intriguing phenomenon by which adjacent cells become sensitized to drug treatment during gene therapy with herpes simplex virus thymidine kinase/ganciclovir (HSV-tk/GCV). This effect is reported to be mediated by gap junctional intercellular communication (GJIC), and there...

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Detalles Bibliográficos
Autores principales:	Xiao, Jianyong, Zhang, Guangxian, Qiu, Pengxiang, Liu, Xijuan, Wu, Yingya, Du, Biaoyan, Li, Jiefen, Zhou, Jing, Li, Jingjing, Tan, Yuhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701623/ https://www.ncbi.nlm.nih.gov/pubmed/23861780 http://dx.doi.org/10.1371/journal.pone.0067662

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