Increased S-Nitrosylation and Proteasomal Degradation of Caspase-3 during Infection Contribute to the Persistence of Adherent Invasive Escherichia coli (AIEC) in Immune Cells

Adherent invasive Escherichia coli (AIEC) have been implicated as a causative agent of Crohn’s disease (CD) due to their isolation from the intestines of CD sufferers and their ability to persist in macrophages inducing granulomas. The rapid intracellular multiplication of AIEC sets it apart from ot...

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Detalles Bibliográficos
Autores principales: Dunne, Karl A., Allam, Amr, McIntosh, Anne, Houston, Stephanie A., Cerovic, Vuk, Goodyear, Carl S., Roe, Andrew J., Beatson, Scott A., Milling, Simon W., Walker, Daniel, Wall, Daniel M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701656/
https://www.ncbi.nlm.nih.gov/pubmed/23861899
http://dx.doi.org/10.1371/journal.pone.0068386

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