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Erosive Arthritis and Hepatic Granuloma Formation Induced by Peptidoglycan Polysaccharide in Rats Is Aggravated by Prasugrel Treatment

Administration of the thienopyridine P2Y(12) receptor antagonist, clopidogrel, increased the erosive arthritis induced by peptidoglycan polysaccharide (PG-PS) in rats or by injection of the arthritogenic K/BxN serum in mice. To determine if the detrimental effects are caused exclusively by clopidogr...

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Detalles Bibliográficos
Autores principales: Garcia, Analia E., Rico, Mario C., Liverani, Elisabetta, DeLa Cadena, Raul A., Bray, Paul F., Kunapuli, Satya P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701687/
https://www.ncbi.nlm.nih.gov/pubmed/23861957
http://dx.doi.org/10.1371/journal.pone.0069093