A Key Role for the Urokinase Plasminogen Activator (uPA) in Invasive Group A Streptococcal Infection

Recruitment of the serine protease plasmin is central to the pathogenesis of many bacterial species, including Group A streptococcus (GAS), a leading cause of morbidity and mortality globally. A key process in invasive GAS disease is the ability to accumulate plasmin at the cell surface, however the...

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Detalles Bibliográficos
Autores principales: Sanderson-Smith, Martina L., Zhang, Yueling, Ly, Diane, Donahue, Deborah, Hollands, Andrew, Nizet, Victor, Ranson, Marie, Ploplis, Victoria A., Walker, Mark J., Castellino, Francis J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701706/
https://www.ncbi.nlm.nih.gov/pubmed/23853591
http://dx.doi.org/10.1371/journal.ppat.1003469

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701706/
https://www.ncbi.nlm.nih.gov/pubmed/23853591
http://dx.doi.org/10.1371/journal.ppat.1003469

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