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The Interactomes of Influenza Virus NS1 and NS2 Proteins Identify New Host Factors and Provide Insights for ADAR1 Playing a Supportive Role in Virus Replication
Influenza A NS1 and NS2 proteins are encoded by the RNA segment 8 of the viral genome. NS1 is a multifunctional protein and a virulence factor while NS2 is involved in nuclear export of viral ribonucleoprotein complexes. A yeast two-hybrid screening strategy was used to identify host factors support...
Autores principales: | de Chassey, Benoît, Aublin-Gex, Anne, Ruggieri, Alessia, Meyniel-Schicklin, Laurène, Pradezynski, Fabrine, Davoust, Nathalie, Chantier, Thibault, Tafforeau, Lionel, Mangeot, Philippe-Emmanuel, Ciancia, Claire, Perrin-Cocon, Laure, Bartenschlager, Ralf, André, Patrice, Lotteau, Vincent |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701712/ https://www.ncbi.nlm.nih.gov/pubmed/23853584 http://dx.doi.org/10.1371/journal.ppat.1003440 |
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