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Alu Elements in ANRIL Non-Coding RNA at Chromosome 9p21 Modulate Atherogenic Cell Functions through Trans-Regulation of Gene Networks
The chromosome 9p21 (Chr9p21) locus of coronary artery disease has been identified in the first surge of genome-wide association and is the strongest genetic factor of atherosclerosis known today. Chr9p21 encodes the long non-coding RNA (ncRNA) antisense non-coding RNA in the INK4 locus (ANRIL). ANR...
Autores principales: | Holdt, Lesca M., Hoffmann, Steve, Sass, Kristina, Langenberger, David, Scholz, Markus, Krohn, Knut, Finstermeier, Knut, Stahringer, Anika, Wilfert, Wolfgang, Beutner, Frank, Gielen, Stephan, Schuler, Gerhard, Gäbel, Gabor, Bergert, Hendrik, Bechmann, Ingo, Stadler, Peter F., Thiery, Joachim, Teupser, Daniel |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701717/ https://www.ncbi.nlm.nih.gov/pubmed/23861667 http://dx.doi.org/10.1371/journal.pgen.1003588 |
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