Cargando…

Identification of Caveolin-1 as a Potential Causative Factor in the Generation of Trastuzumab Resistance in Breast Cancer Cells

The oncogenic tyrosine kinase receptor ErbB2 is a prognostic factor and target for breast cancer therapeutics. In contrast with the other ErbB receptors, ErbB2 is hardly internalized by ligand induced mechanisms, indicating a prevalent surface expression. Elevated levels of ErbB2 in tumor cells are...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sekhar, Sreeja C, Kasai, Tomonari, Satoh, Ayano, Shigehiro, Tsukasa, Mizutani, Akifumi, Murakami, Hiroshi, El-Aarag, Bishoy YA, Salomon, David S., Massaguer, Anna, de Llorens, Rafael, Seno, Masaharu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2013
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701809/ https://www.ncbi.nlm.nih.gov/pubmed/23833684 http://dx.doi.org/10.7150/jca.6470

Ejemplares similares

Efficient Drug Delivery of Paclitaxel Glycoside: A Novel Solubility Gradient Encapsulation into Liposomes Coupled with Immunoliposomes Preparation
por: Shigehiro, Tsukasa, et al.
Publicado: (2014)

Chlorotoxin-Fc Fusion Inhibits Release of MMP-2 from Pancreatic Cancer Cells
por: El-Ghlban, Samah, et al.
Publicado: (2014)

Practical Liposomal Formulation for Taxanes with Polyethoxylated Castor Oil and Ethanol with Complete Encapsulation Efficiency and High Loading Efficiency
por: Shigehiro, Tsukasa, et al.
Publicado: (2017)

Chlorotoxin Fused to IgG-Fc Inhibits Glioblastoma Cell Motility via Receptor-Mediated Endocytosis
por: Kasai, Tomonari, et al.
Publicado: (2012)

Cytokine Expression and Macrophage Localization in Xenograft and Allograft Tumor Models Stimulated with Lipopolysaccharide
por: Masuda, Junko, et al.
Publicado: (2018)

Cancer stem cells maintain a hierarchy of differentiation by creating their niche
por: Matsuda, Shuichi, et al.
Publicado: (2014)

Cancer stem cell induction from mouse embryonic stem cells
por: Seno, Akimasa, et al.
Publicado: (2019)

Characterization of Gene Expression Patterns among Artificially Developed Cancer Stem Cells Using Spherical Self-Organizing Map
por: Seno, Akimasa, et al.
Publicado: (2016)

Characterization of Cancer Stem-Like Cells Derived from Mouse Induced Pluripotent Stem Cells Transformed by Tumor-Derived Extracellular Vesicles
por: Yan, Ting, et al.
Publicado: (2014)

A Model of Cancer Stem Cells Derived from Mouse Induced Pluripotent Stem Cells
por: Chen, Ling, et al.
Publicado: (2012)

A Unique Procedure to Identify Cell Surface Markers Through a Spherical Self-Organizing Map Applied to DNA Microarray Analysis
por: Sugii, Yuh, et al.
Publicado: (2016)

Targeting Glioblastoma Cells Expressing CD44 with Liposomes Encapsulating Doxorubicin and Displaying Chlorotoxin-IgG Fc Fusion Protein
por: Mahmud, Hafizah, et al.
Publicado: (2018)

Enhanced internalization of ErbB2 in SK-BR-3 cells with multivalent forms of an artificial ligand
por: Vaidyanath, Arun, et al.
Publicado: (2011)

Caveolin-3: A Causative Process of Chicken Muscular Dystrophy
por: Kikuchi, Tateki
Publicado: (2020)

Up-Regulation of PI 3-Kinases and the Activation of PI3K-Akt Signaling Pathway in Cancer Stem-Like Cells Through DNA Hypomethylation Mediated by the Cancer Microenvironment
por: Oo, Aung Ko Ko, et al.
Publicado: (2018)

Development of an Epidermal Growth Factor Derivative with EGFR Blocking Activity
por: Panosa, Clara, et al.
Publicado: (2013)

Caveolin-1 mediates cellular distribution of HER2 and affects trastuzumab binding and therapeutic efficacy
por: Pereira, Patrícia M. R., et al.
Publicado: (2018)

Megakaryocytic Emperipolesis Associated with Thrombocytopenia: Causative or Coincidence?
por: Goyal, Manu, et al.
Publicado: (2017)

Cancer Stem Cells Converted from Pluripotent Stem Cells and the Cancerous Niche
por: Kasai, T, et al.
Publicado: (2014)

New phthalimide analog ameliorates CCl(4) induced hepatic injury in mice via reducing ROS formation, inflammation, and apoptosis
por: El-Aarag, Bishoy, et al.
Publicado: (2021)

Daunorubicin can eliminate iPS-derived cancer stem cells via ICAD/CAD-independent DNA fragmentation
por: Seno, Akimasa, et al.
Publicado: (2019)

Protective Effects of Flavone from Tamarix aphylla against CCl(4)-Induced Liver Injury in Mice Mediated by Suppression of Oxidative Stress, Apoptosis and Angiogenesis
por: El-Aarag, Bishoy, et al.
Publicado: (2019)

Caveolin-1 Dependent Endocytosis Enhances the Chemosensitivity of HER-2 Positive Breast Cancer Cells to Trastuzumab Emtansine (T-DM1)
por: Chung, Yuan-Chiang, et al.
Publicado: (2015)

Optimize the combination regimen of Trastuzumab and Nab-paclitaxel in HER2-positive tumors via modulating Caveolin-1 expression by lovastatin
por: Yang, Canyu, et al.
Publicado: (2022)

Immune State Conversion of the Mesenteric Lymph Node in a Mouse Breast Cancer Model
por: Shigehiro, Tsukasa, et al.
Publicado: (2022)

Design, Synthesis, and Antiproliferative Activity of Benzopyran-4-One-Isoxazole Hybrid Compounds
por: Gupta, Shilpi, et al.
Publicado: (2023)

The caveolin proteins
por: Williams, Terence M, et al.
Publicado: (2004)

Caveolins in rhabdomyosarcoma
por: Rossi, Stefania, et al.
Publicado: (2011)

The structural characterization and bioactivity assessment of nonspecific lipid transfer protein 1 (nsLTP1) from caraway (Carum carvi) seeds
por: Aldakhil, Taibah, et al.
Publicado: (2023)

A cancer stem cell model as the point of origin of cancer-associated fibroblasts in tumor microenvironment
por: Nair, Neha, et al.
Publicado: (2017)

Melittin Exerts Beneficial Effects on Paraquat-Induced Lung Injuries in Mice by Modifying Oxidative Stress and Apoptosis
por: El-Aarag, Bishoy, et al.
Publicado: (2019)

Caveolin-2 associates with intracellular chlamydial inclusions independently of caveolin-1
por: Webley, Wilmore C, et al.
Publicado: (2004)

Caveolin-1 and Caveolin-2 Can Be Antagonistic Partners in Inflammation and Beyond
por: de Almeida, Cecília Jacques Gonçalves
Publicado: (2017)

The liver that caveolin built
por: Wells, William A.
Publicado: (2006)

Cripto-1 as a Potential Target of Cancer Stem Cells for Immunotherapy
por: Ishii, Hiroko, et al.
Publicado: (2021)

Synthesis, Characterization, and In Vivo Anti-Cancer Activity of New Metal Complexes Derived from Isatin-N(4)antipyrinethiosemicarbazone Ligand Against Ehrlich Ascites Carcinoma Cells
por: El-Saied, Fathy, et al.
Publicado: (2019)

Causation
Publicado: (1993)

Induction of caveolin during adipogenesis and association of GLUT4 with caveolin-rich vesicles
Publicado: (1994)

Causation and disease: effect of technology on postulates of causation.
por: Evans, A. S.
Publicado: (1991)

Exendin-4 ameliorates cardiac ischemia/reperfusion injury via caveolae and caveolins-3
por: Tsutsumi, Yasuo M, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_l6jipnu6gko53jvl3rpauj53ok