Identification of Two Maternal Transmission Ratio Distortion Loci in Pedigrees of the Framingham Heart Study

Transmission ratio distortion (TRD) is indicated by the recovery of alleles in offspring in non-Mendelian proportions. An assumption of Mendelian proportion is central to many methods to identify disease-associated markers. This seems reasonable as, while TRD cases have been occasionally observed in...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Zhang, Liangliang, Xu, Shuhua, Hu, Landian, Hurst, Laurence D., Kong, Xiangyin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701898/
https://www.ncbi.nlm.nih.gov/pubmed/23828458
http://dx.doi.org/10.1038/srep02147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701898/
https://www.ncbi.nlm.nih.gov/pubmed/23828458
http://dx.doi.org/10.1038/srep02147

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