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Identification of Two Maternal Transmission Ratio Distortion Loci in Pedigrees of the Framingham Heart Study
Transmission ratio distortion (TRD) is indicated by the recovery of alleles in offspring in non-Mendelian proportions. An assumption of Mendelian proportion is central to many methods to identify disease-associated markers. This seems reasonable as, while TRD cases have been occasionally observed in...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701898/ https://www.ncbi.nlm.nih.gov/pubmed/23828458 http://dx.doi.org/10.1038/srep02147 |