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Diabetic Ketoacidosis Presenting with Pseudonormoglycemia in a 15-Year-Old Girl with Type 1 Diabetes Mellitus

Pseudonormoglycemic diabetic ketoacidosis (DKA) is a rare condition and has been reported only in a few adult patients. We present a 15-year-old girl with a 9-year history of type 1 diabetes who presented with euglycemic and extreme hypertriglyceridemia. The acidosis and hypertriglyceridemia resolve...

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Autores principales: Akbay, Sinem, Yel, Arda, Yıldırımer, Ülkü, Can, Şule, Dündar, Bumin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701921/
https://www.ncbi.nlm.nih.gov/pubmed/23748069
http://dx.doi.org/10.4274/Jcrpe.905
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author Akbay, Sinem
Yel, Arda
Yıldırımer, Ülkü
Can, Şule
Dündar, Bumin
author_facet Akbay, Sinem
Yel, Arda
Yıldırımer, Ülkü
Can, Şule
Dündar, Bumin
author_sort Akbay, Sinem
collection PubMed
description Pseudonormoglycemic diabetic ketoacidosis (DKA) is a rare condition and has been reported only in a few adult patients. We present a 15-year-old girl with a 9-year history of type 1 diabetes who presented with euglycemic and extreme hypertriglyceridemia. The acidosis and hypertriglyceridemia resolved with intravenous insulin therapy and rehydration. Hyperlipidemia was the apparent cause of pseudonormoglycemia in this patient. The findings in the present case demonstrate that also in children, DKA can rarely occur without abnormal blood glucose levels. Assessment of the acid-base status, urinary glucose, and ketone readings is therefore important in all diabetic patients who are unwell at admission and have normal glucose levels. In such patients, hyperlipidemia may cause pseudonormoglycemia. An awareness of this rare treatable life-threatening condition is important. Conflict of interest:None declared.
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spelling pubmed-37019212013-07-12 Diabetic Ketoacidosis Presenting with Pseudonormoglycemia in a 15-Year-Old Girl with Type 1 Diabetes Mellitus Akbay, Sinem Yel, Arda Yıldırımer, Ülkü Can, Şule Dündar, Bumin J Clin Res Pediatr Endocrinol Case Report Pseudonormoglycemic diabetic ketoacidosis (DKA) is a rare condition and has been reported only in a few adult patients. We present a 15-year-old girl with a 9-year history of type 1 diabetes who presented with euglycemic and extreme hypertriglyceridemia. The acidosis and hypertriglyceridemia resolved with intravenous insulin therapy and rehydration. Hyperlipidemia was the apparent cause of pseudonormoglycemia in this patient. The findings in the present case demonstrate that also in children, DKA can rarely occur without abnormal blood glucose levels. Assessment of the acid-base status, urinary glucose, and ketone readings is therefore important in all diabetic patients who are unwell at admission and have normal glucose levels. In such patients, hyperlipidemia may cause pseudonormoglycemia. An awareness of this rare treatable life-threatening condition is important. Conflict of interest:None declared. Galenos Publishing 2013-06 2013-05-30 /pmc/articles/PMC3701921/ /pubmed/23748069 http://dx.doi.org/10.4274/Jcrpe.905 Text en © Journal of Clinical Research in Pediatric Endocrinology, Published by Galenos Publishing. http://creativecommons.org/licenses/by/2.5/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Akbay, Sinem
Yel, Arda
Yıldırımer, Ülkü
Can, Şule
Dündar, Bumin
Diabetic Ketoacidosis Presenting with Pseudonormoglycemia in a 15-Year-Old Girl with Type 1 Diabetes Mellitus
title Diabetic Ketoacidosis Presenting with Pseudonormoglycemia in a 15-Year-Old Girl with Type 1 Diabetes Mellitus
title_full Diabetic Ketoacidosis Presenting with Pseudonormoglycemia in a 15-Year-Old Girl with Type 1 Diabetes Mellitus
title_fullStr Diabetic Ketoacidosis Presenting with Pseudonormoglycemia in a 15-Year-Old Girl with Type 1 Diabetes Mellitus
title_full_unstemmed Diabetic Ketoacidosis Presenting with Pseudonormoglycemia in a 15-Year-Old Girl with Type 1 Diabetes Mellitus
title_short Diabetic Ketoacidosis Presenting with Pseudonormoglycemia in a 15-Year-Old Girl with Type 1 Diabetes Mellitus
title_sort diabetic ketoacidosis presenting with pseudonormoglycemia in a 15-year-old girl with type 1 diabetes mellitus
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3701921/
https://www.ncbi.nlm.nih.gov/pubmed/23748069
http://dx.doi.org/10.4274/Jcrpe.905
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