Ras inhibition enhances autophagy, which partially protects cells from death

Autophagy, a process of regulated turnover of cellular constituents, is essential for normal growth control but may be defective under pathological conditions. The Ras/PI3K/mTOR signaling pathway negatively regulates autophagy. Ras signaling has been documented in a large number of human cancers. In...

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Detalles Bibliográficos
Autores principales: Schmukler, Eran, Grinboim, Efrat, Schokoroy, Sari, Amir, Adva, Wolfson, Eya, Kloog, Yoel, Pinkas-Kramarski, Ronit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2013
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702214/
https://www.ncbi.nlm.nih.gov/pubmed/23370967

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702214/
https://www.ncbi.nlm.nih.gov/pubmed/23370967

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