Organopalladium compound 7b targets mitochondrial thiols and induces caspase-dependent apoptosis in human myeloid leukemia cells

The advances in the treatment of chronic myeloid leukemia (CML) during the last years were also accompanied by the development of evading strategies by tumor cells, resulting in chemotherapy resistance in some patients. Patented organopalladium compounds derived from the reaction of N,N-dimethyl-1-p...

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Detalles Bibliográficos
Autores principales: Moraes, V W R, Caires, A C F, Paredes-Gamero, E J, Rodrigues, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702286/
https://www.ncbi.nlm.nih.gov/pubmed/23744358
http://dx.doi.org/10.1038/cddis.2013.190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702286/
https://www.ncbi.nlm.nih.gov/pubmed/23744358
http://dx.doi.org/10.1038/cddis.2013.190

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