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The embryonic transcription factor Brachyury blocks cell cycle progression and mediates tumor resistance to conventional antitumor therapies

The T-box transcription factor Brachyury, a molecule frequently detected in human cancers but seldom found in normal adult tissue, has recently been characterized as a driver of the epithelial-to-mesenchymal switch of human carcinomas. In the current investigation, we present data demonstrating that...

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Detalles Bibliográficos
Autores principales:	Huang, B, Cohen, J R, Fernando, R I, Hamilton, D H, Litzinger, M T, Hodge, J W, Palena, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702290/ https://www.ncbi.nlm.nih.gov/pubmed/23788039 http://dx.doi.org/10.1038/cddis.2013.208

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