Pleiotropic actions of miR-21 highlight the critical role of deregulated stromal microRNAs during colorectal cancer progression

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The oncogene microRNA-21 (miRNA; miR-21) is overexpressed in most solid organ tumours; however, a recent examination of stage II colorectal cancer (CRC) specimens suggests this may be a stromal phenomenon and not only a feature of cancer cells. In vitro and in vivo studies show that miR-21 has poten...

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Detalles Bibliográficos
Autores principales: Bullock, M D, Pickard, K M, Nielsen, B S, Sayan, A E, Jenei, V, Mellone, M, Mitter, R, Primrose, J N, Thomas, G J, Packham, G K, Mirenzami, A H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702298/
https://www.ncbi.nlm.nih.gov/pubmed/23788041
http://dx.doi.org/10.1038/cddis.2013.213

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