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A proapoptotic effect of valproic acid on progenitors of embryonic stem cell-derived glutamatergic neurons

Valproic acid (VPA) is a branched-chain saturated fatty acid with a long history of clinical use as an antiepileptic drug (AED). VPA is also known to inhibit histone deacetylases (HDACs) and to cause diverse effects on neural progenitor cells (NPCs) and neurons. Although the neuroprotective or neuro...

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Detalles Bibliográficos
Autores principales:	Fujiki, R, Sato, A, Fujitani, M, Yamashita, T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702299/ https://www.ncbi.nlm.nih.gov/pubmed/23788034 http://dx.doi.org/10.1038/cddis.2013.205

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