N-heteroatom substitution effect in 3-aza-cope rearrangements

BACKGROUND: The nature of the heteroatom substitution in the nitrogen of a 3-aza-Cope system is explored. RESULTS: While N-propargyl isoxazolin-5-ones suffer 3-aza-Cope rearrangements at 60°C, the corresponding N-propargyl pyrazol-5-ones need a higher temperature of 180°C for the equivalent reaction...

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Detalles Bibliográficos
Autores principales: Gomes, Mário JS, Pinto, Luis FV, Glória, Paulo MC, Rzepa, Henry S, Prabhakar, Sundaresan, Lobo, Ana M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702470/
https://www.ncbi.nlm.nih.gov/pubmed/23714005
http://dx.doi.org/10.1186/1752-153X-7-94

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702470/
https://www.ncbi.nlm.nih.gov/pubmed/23714005
http://dx.doi.org/10.1186/1752-153X-7-94

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