Label Free Fragment Screening Using Surface Plasmon Resonance as a Tool for Fragment Finding – Analyzing Parkin, a Difficult CNS Target

Surface Plasmon Resonance (SPR) is rarely used as a primary High-throughput Screening (HTS) tool in fragment-based approaches. With SPR instruments becoming increasingly high-throughput it is now possible to use SPR as a primary tool for fragment finding. SPR becomes, therefore, a valuable tool in t...

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Detalles Bibliográficos
Autores principales: Regnström, Karin, Yan, Jiangli, Nguyen, Lan, Callaway, Kari, Yang, Yanli, Diep, Linnea, Xing, Weimei, Adhikari, Anirban, Beroza, Paul, Hom, Roy K., Riley, Brigit, Rudolph, Don, Jobling, Michael F., Baker, Jeanne, Johnston, Jennifer, Konradi, Andrei, Bova, Michael P., Artis, Rick D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702509/
https://www.ncbi.nlm.nih.gov/pubmed/23861750
http://dx.doi.org/10.1371/journal.pone.0066879

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