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Conformational Dynamics of a Ligand-Free Adenylate Kinase
Adenylate kinase (AdK) is a phosphoryl-transfer enzyme with important physiological functions. Based on a ligand-free open structure and a ligand-bound closed structure solved by crystallography, here we use molecular dynamics simulations to examine the stability and dynamics of AdK conformations in...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2013
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702565/ https://www.ncbi.nlm.nih.gov/pubmed/23861846 http://dx.doi.org/10.1371/journal.pone.0068023 |