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Genetic Variability in Markers of HLA-C Expression in Two Diverse South African Populations
An insertion-deletion (indel) polymorphism within the 3′ untranslated region (UTR) of HLA-C has been shown to be involved in the regulation of HLA-C expression. Individuals who carry a deletion at this position exhibit increased HLA-C expression, which associates with lower viral set point in HIV-1...
Autores principales: | Gentle, Nikki L., Paximadis, Maria, Puren, Adrian, Tiemessen, Caroline T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702582/ https://www.ncbi.nlm.nih.gov/pubmed/23861805 http://dx.doi.org/10.1371/journal.pone.0067780 |
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