Cargando…

Alpha-Linolenic Acid Exerts an Endothelial Protective Effect against High Glucose Injury via PI3K/Akt Pathway

Mounting evidence has indicated that the cardiovascular protective effects of dietary alpha-linolenic acid (ALA), but whether ALA exerts an endothelial protective effect against high glucose injury and the underlying mechanisms remain largely unknown. Streptozocin-induced diabetic rats were randomiz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Wei, Li, Rong, Li, Jia, Wang, Wenqing, Tie, Ru, Tian, Fei, Liang, Xiangyan, Xing, Wenjuan, He, Yong, Yu, Liang, Xi, Miaomiao, Wang, Siwang, Zheng, Qiangsun, Zhang, Haifeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702615/ https://www.ncbi.nlm.nih.gov/pubmed/23861910 http://dx.doi.org/10.1371/journal.pone.0068489

Ejemplares similares

Achyranthes bidentata Polypeptides Reduces Oxidative Stress and Exerts Protective Effects against Myocardial Ischemic/Reperfusion Injury in Rats
por: Tie, Ru, et al.
Publicado: (2013)

Multi-Omics Analysis of Genes Encoding Proteins Involved in Alpha-Linolenic Acid Metabolism in Chicken
por: Zhao, Wenjuan, et al.
Publicado: (2023)

Alpha-Linolenic Acid: Is It Essential to Cardiovascular Health?
por: Geleijnse, Johanna M., et al.
Publicado: (2010)

Anti-thrombotic effects of α-linolenic acid isolated from Zanthoxylum bungeanum Maxim seeds
por: Yang, Qian, et al.
Publicado: (2014)

Genotoxicity evaluation of alpha-linolenic acid-diacylglycerol oil
por: Honda, Hiroshi, et al.
Publicado: (2016)

β-Hydroxyisovaleryl-Shikonin Exerts an Antitumor Effect on Pancreatic Cancer Through the PI3K/AKT Signaling Pathway
por: Zeng, Yu, et al.
Publicado: (2022)

Is there A Role for Alpha-Linolenic Acid in the Fetal Programming of Health?
por: Leikin-Frenkel, Alicia I.
Publicado: (2016)

Alpha-Linolenic Acid and Cardiovascular Events: A Narrative Review
por: Bertoni, Camilla, et al.
Publicado: (2023)

Effect of 1‐ and 2‐Month High‐Dose Alpha‐Linolenic Acid Treatment on (13)C‐Labeled Alpha‐Linolenic Acid Incorporation and Conversion in Healthy Subjects
por: Pignitter, Marc, et al.
Publicado: (2018)

α-Linolenic acid but not linolenic acid protects against hypertension: critical role of SIRT3 and autophagic flux
por: Li, Guohua, et al.
Publicado: (2020)

Gamma Linolenic Acid Exerts Anti-Inflammatory and Anti-Fibrotic Effects in Diabetic Nephropathy
por: Kim, Do-Hee, et al.
Publicado: (2012)

Sanbai Melon Seed Oil Exerts Its Protective Effects in a Diabetes Mellitus Model via the Akt/GSK-3β/Nrf2 Pathway
por: Wang, Fang, et al.
Publicado: (2019)

Alternative Splicing Analysis Revealed the Role of Alpha-Linolenic Acid and Carotenoids in Fruit Development of Osmanthus fragrans
por: Ma, Cancan, et al.
Publicado: (2023)

AMP-activated protein kinase is required for the anti-adipogenic effects of alpha-linolenic acid
por: Zhou, Xihong, et al.
Publicado: (2015)

Effect of Alpha-Linolenic Acid on Oocyte Maturation and Embryo Development in Pigs
por: Lee, Ji-Eun, et al.
Publicado: (2017)

Dietary Alpha-Linolenic Acid Supports High Retinal DHA Levels
por: Sinclair, Andrew J., et al.
Publicado: (2022)

Alpha‐linolenic acid given as an anti‐inflammatory agent in a mouse model of colonic inflammation
por: Wen, Juan, et al.
Publicado: (2019)

Phlorizin Exerts Direct Protective Effects on Palmitic Acid (PA)-Induced Endothelial Dysfunction by Activating the PI3K/AKT/eNOS Signaling Pathway and Increasing the Levels of Nitric Oxide (NO)
por: Li, Chun-Ying, et al.
Publicado: (2018)

Antitumor Activity of α-Linolenic Acid-Paclitaxel Conjugate Nanoparticles: In vitro and in vivo
por: Xu, Mei-Qi, et al.
Publicado: (2021)

The Alpha Linolenic Acid Content of Flaxseed is Associated with an Induction of Adipose Leptin Expression
por: McCullough, Richelle S., et al.
Publicado: (2011)

Nitric oxide secretion in human conjunctival fibroblasts is inhibited by alpha linolenic acid
por: Erdinest, Nir, et al.
Publicado: (2015)

Circulating linoleic acid and alpha-linolenic acid and glucose metabolism: the Hoorn Study
por: Cabout, Mieke, et al.
Publicado: (2016)

The impact of liposomal linolenic acid on gastrointestinal microbiota in mice
por: Li, Xuan-xuan, et al.
Publicado: (2018)

Gynura divaricata exerts hypoglycemic effects by regulating the PI3K/AKT signaling pathway and fatty acid metabolism signaling pathway
por: Xu, Wenjun, et al.
Publicado: (2020)

Fangchinoline exerts antitumour activity by suppressing the EGFR-PI3K/AKT signalling pathway in colon adenocarcinoma
por: Jiang, Fengqi, et al.
Publicado: (2021)

Digoxin exerts anticancer activity on human nonsmall cell lung cancer cells by blocking PI3K/Akt pathway
por: Wang, Yingying, et al.
Publicado: (2021)

Dietary α-Linolenic Acid-Rich Flaxseed Oil Exerts Beneficial Effects on Polycystic Ovary Syndrome Through Sex Steroid Hormones—Microbiota—Inflammation Axis in Rats
por: Wang, Ting, et al.
Publicado: (2020)

Estrogen Receptor and PI3K/Akt Signaling Pathway Involvement in S-(-)Equol-Induced Activation of Nrf2/ARE in Endothelial Cells
por: Zhang, Ting, et al.
Publicado: (2013)

Dietary Ground Flaxseed Increases Serum Alpha-Linolenic Acid Concentrations in Adult Cats
por: Panasevich, Matthew R., et al.
Publicado: (2022)

Identification of the alpha linolenic acid metabolism-related signature associated with prognosis and the immune microenvironment in nasopharyngeal carcinoma
por: Fang, Zhijie, et al.
Publicado: (2022)

Terpenoid natural products exert neuroprotection via the PI3K/Akt pathway
por: Xu, Bingyao, et al.
Publicado: (2022)

Effect of Alpha Linolenic Acid Supplementation on Serum Prostate Specific Antigen (PSA): Results from the Alpha Omega Trial
por: Brouwer, Ingeborg A., et al.
Publicado: (2013)

Apolipoprotein M and sphingosine-1-phosphate complex alleviates TNF-α-induced endothelial cell injury and inflammation through PI3K/AKT signaling pathway
por: Liu, Yang, et al.
Publicado: (2019)

Polygonum cuspidatum Extract Exerts Antihyperlipidemic Effects by Regulation of PI3K/AKT/FOXO3 Signaling Pathway
por: Tao, Ting, et al.
Publicado: (2021)

TPX2 silencing exerts anti-tumor effects on hepatocellular carcinoma by regulating the PI3K/AKT signaling pathway
por: Huang, Dan-Hong, et al.
Publicado: (2019)

The effect of alpha linolenic acid on tracheal responsiveness, lung inflammation, and immune markers in sensitized rats
por: Kaveh, Mahsa, et al.
Publicado: (2019)

Alpha-Linolenic Acid Impedes Cadmium-Induced Oxidative Stress, Neuroinflammation, and Neurodegeneration in Mouse Brain
por: Alam, Sayed-Ibrar, et al.
Publicado: (2021)

TSPAN7 Exerts Anti-Tumor Effects in Bladder Cancer Through the PTEN/PI3K/AKT Pathway
por: Yu, Xi, et al.
Publicado: (2021)

TCM Regulates PI3K/Akt Signal Pathway to Intervene Atherosclerotic Cardiovascular Disease
por: Liu, Jiali, et al.
Publicado: (2021)

MicroRNA-1231 exerts a tumor suppressor role through regulating the EGFR/PI3K/AKT axis in glioma
por: Zhang, Jiale, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_1sa4vc5o8r1mnv40t5e8491r52