Homeostatic control of Argonaute stability by microRNA availability

Homeostatic mechanisms regulate the abundance of many small RNA components. We used Drosophila and mammalian systems to demonstrate a conserved homeostatic system in which the status of miRNA biogenesis controls Argonaute protein stability. Clonal analyses of multiple mutants of core Drosophila miRN...

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Detalles Bibliográficos
Autores principales: Smibert, Peter, Yang, Jr-Shiuan, Azzam, Ghows, Liu, Ji-Long, Lai, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702675/
https://www.ncbi.nlm.nih.gov/pubmed/23708604
http://dx.doi.org/10.1038/nsmb.2606

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702675/
https://www.ncbi.nlm.nih.gov/pubmed/23708604
http://dx.doi.org/10.1038/nsmb.2606

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