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Homeostatic control of Argonaute stability by microRNA availability
Homeostatic mechanisms regulate the abundance of many small RNA components. We used Drosophila and mammalian systems to demonstrate a conserved homeostatic system in which the status of miRNA biogenesis controls Argonaute protein stability. Clonal analyses of multiple mutants of core Drosophila miRN...
Autores principales: | Smibert, Peter, Yang, Jr-Shiuan, Azzam, Ghows, Liu, Ji-Long, Lai, Eric C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702675/ https://www.ncbi.nlm.nih.gov/pubmed/23708604 http://dx.doi.org/10.1038/nsmb.2606 |
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