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Gender-dependent miR-375 promoter methylation and the risk of type 2 diabetes

Promoter DNA methylation may reflect the interaction between genetic background and environmental factors in the development of metabolic disorders, including type 2 diabetes (T2D). As an epigenetic factor of T2D, miR-375 plays an important role in the functional accommodation of islet cells. In the...

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Detalles Bibliográficos
Autores principales: CHENG, JIA, WANG, LINGYAN, XU, LEITING, WANG, HONGWEI, LIU, PANPAN, BU, SHIZHONG, YE, MENG, ZHANG, LINA, WANG, QINWEN, DUAN, SHIWEI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702700/
https://www.ncbi.nlm.nih.gov/pubmed/23837055
http://dx.doi.org/10.3892/etm.2013.1069