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7,8-Dihydroxycoumarin inhibits A549 human lung adenocarcinoma cell proliferation by inducing apoptosis via suppression of Akt/NF-κB signaling

The Akt/NF-κB pathways are involved in numerous anti-apoptotic and drug-resistance events that occur in non-small cell lung cancer (NSCLC). In the present study, the role of 7,8-dihydroxycoumarin in the regulation of the anti-apoptotic Akt and NF-κBp65 signaling pathways was explored. A549 human lun...

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Detalles Bibliográficos
Autores principales:	WANG, YUE, LI, CHANG-FENG, PAN, LI-MING, GAO, ZHONG-LI
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2013
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3702713/ https://www.ncbi.nlm.nih.gov/pubmed/23837071 http://dx.doi.org/10.3892/etm.2013.1054

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