Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children

In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise...

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Detalles Bibliográficos
Autores principales: Nicol, Mark P., Spiers, Karalene, Workman, Lesley, Isaacs, Washiefa, Munro, Jacinta, Black, Faye, Zemanay, Widaad, Zar, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Electronic Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703104/
https://www.ncbi.nlm.nih.gov/pubmed/23580738
http://dx.doi.org/10.1093/cid/cit230
Descripción
Sumario:In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children.

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