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Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children

In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise...

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Autores principales: Nicol, Mark P., Spiers, Karalene, Workman, Lesley, Isaacs, Washiefa, Munro, Jacinta, Black, Faye, Zemanay, Widaad, Zar, Heather J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703104/
https://www.ncbi.nlm.nih.gov/pubmed/23580738
http://dx.doi.org/10.1093/cid/cit230
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author Nicol, Mark P.
Spiers, Karalene
Workman, Lesley
Isaacs, Washiefa
Munro, Jacinta
Black, Faye
Zemanay, Widaad
Zar, Heather J.
author_facet Nicol, Mark P.
Spiers, Karalene
Workman, Lesley
Isaacs, Washiefa
Munro, Jacinta
Black, Faye
Zemanay, Widaad
Zar, Heather J.
author_sort Nicol, Mark P.
collection PubMed
description In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children.
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spelling pubmed-37031042014-06-09 Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children Nicol, Mark P. Spiers, Karalene Workman, Lesley Isaacs, Washiefa Munro, Jacinta Black, Faye Zemanay, Widaad Zar, Heather J. Clin Infect Dis Electronic Article In a pilot accuracy study, stool Xpert testing from 115 children with suspected pulmonary tuberculosis (PTB) detected 8/17 (47%) culture-confirmed tuberculosis cases, including 4/5 (80%) HIV-infected and 4/12 (33%) HIV-uninfected children. Sputum Xpert detected 11/17 (65%) cases. Stool holds promise for PTB diagnosis in HIV-infected children. Oxford University Press 2013-08-01 2013-04-11 /pmc/articles/PMC3703104/ /pubmed/23580738 http://dx.doi.org/10.1093/cid/cit230 Text en © The Author 2013. Published by Oxford University Press on behalf of the Infectious Diseases Society of America. http://creativecommons.org/licenses/by/3.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Electronic Article
Nicol, Mark P.
Spiers, Karalene
Workman, Lesley
Isaacs, Washiefa
Munro, Jacinta
Black, Faye
Zemanay, Widaad
Zar, Heather J.
Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children
title Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children
title_full Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children
title_fullStr Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children
title_full_unstemmed Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children
title_short Xpert MTB/RIF Testing of Stool Samples for the Diagnosis of Pulmonary Tuberculosis in Children
title_sort xpert mtb/rif testing of stool samples for the diagnosis of pulmonary tuberculosis in children
topic Electronic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703104/
https://www.ncbi.nlm.nih.gov/pubmed/23580738
http://dx.doi.org/10.1093/cid/cit230
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