Pregabalin for Opioid-Refractory Pain in a Patient with Ankylosing Spondylitis

Background. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opi...

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Detalles Bibliográficos
Autores principales: Kontoangelos, Konstantinos A., Kouzoupis, Anastasios V., Ferentinos, Panagiotis P., Xynos, Ioannis D., Sipsas, Nikolaos V., Papadimitriou, George N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703399/
https://www.ncbi.nlm.nih.gov/pubmed/23844301
http://dx.doi.org/10.1155/2013/912409
Descripción
Sumario:Background. Ankylosing spondylitis (AS) is a systemic inflammatory disease with chronic back pain as the most common presenting symptom. We present a case of a male patient with AS reporting symptoms of severe low back pain, buttock pain, and limited spinal mobility. After chronic treatment with opioids, we administered pregabalin at a dose of 300 mg as an analgesic agent while opioids were discontinued. Findings. Pain symptoms improved progressively, and opioids were gradually discontinued without any withdrawal symptoms reported. Conclusions. Pregabalin is potentially useful in the management of pain in patients with AS while effectively managing the discontinuation of opioid treatment.

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